Examines Critical Decisions for Transitioning Lab Science to a Clinical Setting The development of therapeutic pharmaceutical compounds is becoming more expensive, and the success rates for getting such treatments approved for marketing and to the patients is decreasing. As a result, translational medicine (TM) is becoming increasingly important in the healthcare industry - a means of maximizing the consideration and use of information collected as compounds transition from initial lab discovery, through pre-clinical testing, early clinical trials, and late confirmatory studies that lead to regulatory approval of drug release to patients. Translational Medicine: Strategies and Statistical Methods suggests a process for transitioning from the initial lab discovery to the patient's bedside with minimal disconnect and offers a comprehensive review of statistical design and methodology commonly employed in this bench-to-bedside research. Documents Alternative Research Approaches for Faster and More Accurate Data Judgment Calls Elaborating on how to introduce TM into clinical studies, this authoritative work presents a keen approach to building, executing, and validating statistical models that consider data from various phases of development. It also delineates a truly translational example to help bolster understanding of discussed concepts. This comprehensive guide effectively demonstrates how to overcome obstacles related to successful TM practice. It contains invaluable information for pharmaceutical scientists, research executives, clinicians, and biostatisticians looking to expedite successful implementation of this important process.
Product Identifiers
Publisher
CRC Press LLC
ISBN-10
0367386178
ISBN-13
9780367386177
eBay Product ID (ePID)
3038288102
Product Key Features
Author
Shein-Chung Chow
Publication Name
Translational Medicine
Format
Trade Paperback
Language
English
Publication Year
2019
Type
Textbook
Number of Pages
224 Pages
Dimensions
Item Length
9.2in
Item Width
6.2in
Item Weight
15.9 Oz
Additional Product Features
Table of Content
Translational Medicine: Strategies and Statistical Methods. Strategic Concepts in Translational Medicine. Design and Analysis Approaches for Discovery Translational Medicine. Biomarker Development. Targeted Clinical Trials. Statistical Methods in Translational Medicine. NonparametricMethods in Translational Research. Model Selection/Validation. Translation in Clinical Information between Populations--Bridging Studies. Translation in Clinical Technology--Traditional Chinese Medicine. Index.