RARE "tuberculosis" Eugene Lindsay Opie Hand Written Letter

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RARE "tuberculosis" Eugene Lindsay Opie Hand Written Letter:
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Up for sale a RARE! "tuberculosis" Eugene Lindsay Opie Hand Written Letter.

March 12, 1971) was research on the causes, transmission, and diagnosis of tuberculosis and on immunization against the disease. He

served as professor of pathology at several U.S. medical schools and as Dean of

the Washington University School of Medicine (St. Louis, Missouri). Opie was born in Staunton, Virginia, on July 5, 1873. His father, Thomas, was an obstetrician-gynecologist, and one of the founders and deans of the University of Maryland College of Medicine in Baltimore. Eugene attended Johns Hopkins University, both as an undergraduate and a medical student. He received

an A.B. degree in 1893, and was in the first graduating class

of the Johns Hopkins Medical School, earning the M.D. degree in 1897.

Under the tutelage of the pathologist William H. Welch, Opie developed a special affinity for tissue

pathology. As a medical student, he observed consistent morphological

alterations in the pancreatic islets of Langerhans in

patients with diabetes mellitus – an observational

epiphany that shed light on the pathogenesis of that disease. Opie stayed on at

Johns Hopkins after completing medical school, to receive additional training

in pathology from Welch. He continued his work on pancreatic diseases,

establishing the relationship between obstruction of the ampulla of Vater (e.g., by gallstones) and the subsequent development of acute pancreatitis. In 1904, Opie moved to New York City to work at the Rockefeller Institute,

with a focus on the enzymatic constituents of leukocytes and

their role in inflammatory conditions He concurrently served as a

"visiting" pathologist and was named an editor of the Journal of

Experimental Medicine and the Proceedings of the Society for

Experimental Biology. In 1910, Opie was appointed Chair of School of Medicine (WUSM) in St. Louis. He served as Dean of the school from 1912 to 1915, presiding over a

significant expansion of its physical facilities, scientific mission, and

curriculum. When the United States entered World War I, Opie took a leave of absence from WUSM to enter

the U.S. Army. He served in France as a colonel (O6) in the Medical Corps,

with special work on infectious diseases and

their prevention among allied soldiers. Significant new data were and "trench fever" (bartonellosis) during that time.[8] Upon returning to civilian life, Opie continued

his duties at WUSM until 1923. Opie narrowed his general interest in infectious

disease to focus on tuberculosis, an international scourge in the early part of

the 20th century. In 1923 he became the Director of the Phipps Institute for

the Study and Treatment of Tuberculosis at the University of Pennsylvania in Philadelphia. A concomitant appointment as Professor of

Pathology was also given to him. Through Opie's work over the next decade, much

was learned about the modes of tuberculous infection in children and adults, as

well as aspects of immunity, hypersensitivity, and cellular defenses regarding that

disease. Opie moved to Cornell University Medical

Center in New York in 1932 to continue his research. There, as chair of the

Pathology department, he recruited several young pathologists—including Robert

A. Moore, D. Murray Angevine, Jules Freund, and others – who would all go on to

distinguish themselves as renowned investigators in their own rights. Like Opie, Moore also served as chair of

pathology and dean of the medical school at Washington University in the 1940s

and 1950s.